碳纳米管作为载体在生物医学中的研究进展

随着人们对纳米技术的深入探索,各种纳米材料被广泛应用于生物医学领域中.其中碳纳米管(carbon nanotubes,CNTs)具有体积小、比表面积高等独特的物理化学性质,能够吸附或偶联生物大分子或药物,并可穿透细胞膜,有效跨越生物屏障,发挥了其作为载体的特性,在蛋白质、基因和药物传递方面具有广阔的应用前景,受到越来越...

Research Progress of Carbon Nanotubes as Carriers in Biomedical Sciences

With continuous research of nanotechnology,various nano materials are widely used in biomedical field.Carbon nanotubes(CNTs),with unique physicochemical properties such as small volume and high specific surface area,could adsorb or couple biological macromolecules or drugs,penetrate cytomembrane,effectively cross biological barriers,and play the characteristics as carriers,which would be widely used in the areas of protein,gene and drug delivery,and are increasingly concerned by more researchers.As a new nano material,the dispersion,stability and histocompatibility of CNTs in solution could be further improved through functionalization in the future,so as to maximize the coupling rate and activity with biomolecules and further effectively utilize CNTs.In the paper,the properties and functionalization of CNTs as well as the research progress on their role of transporting nucleic acids,genes,proteins and drugs as carriers were summarized,with a view to providing a reference for their application as carriers in the biomedical area.