氯苯胍在鸡组织中的残留消除规律研究 |
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引用本文: | 班付国,吴宁鹏. 氯苯胍在鸡组织中的残留消除规律研究[J]. 中国兽药杂志, 2012, 46(11): 24-26 |
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作者姓名: | 班付国 吴宁鹏 |
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作者单位: | 河南省兽药监察所,郑州,450008 |
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摘 要: | 采用超高效液相色谱一串联质谱法(UPLC-MS/MS)研究了氯苯胍在鸡组织中的残留消除规律。白来杭鸡以含氯苯胍500mg/kg饲料饲喂7d,停药后的第0、1、3、5、7天取其肌肉、肝脏、肾脏、皮和脂肪五种组织,采用UPLC-MS/MS法测定其残留状况。结果表明,氯苯胍在肌肉中残留量较小,代谢消除比较快,2d后未检出;而在脂肪、皮和肝脏中残留量较大,代谢消除较慢。
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关 键 词: | 氯苯胍 鸡组织 残留消除 |
收稿时间: | 2012-05-17 |
修稿时间: | 2012-07-04 |
Depletion of Robenidine Residue in Chicken Tissues |
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Affiliation: | Henan Institute of Veterinary Drug Control, |
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Abstract: | The depletion of robenidine residue in chicken tissues was studied by UPLC - MS/MS. After an oral dose of 500 mg per kilogram of robenidine for 7 days, the robenidine residue in chicken muscle was lower than that in other tissues, such as the fat, skin, kindey and liver, and it was not detected after 2 days. The results showed that robenidine in chicken tissues was of rapid absorption, and hard to be eliminate. |
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Keywords: | robenidine chicken tissues residue depletion |
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