烟丝结构对主流烟气中NNK逐口释放量的影响

为研究卷烟主流烟气中NNK的逐口释放量与烟丝结构间的关系，设计制作不同烟叶类型和烟丝组成的卷烟样品。通过RM20 H吸烟机连接逐口抽吸单元实现对主流烟气粒相物的自动化逐口捕集，并参照烟草总公司标准运用HPLC-MS/MS实现对NNK释放量的定量及变化趋势分析。结果表明：（1）烟丝结构对卷烟NNK的总释放量具有较大影响，调整烟丝配方及降低白肋烟比例可以有效减少NNK的总释放量。（2） NNK的逐口释放量随抽吸口序增加呈线性增加趋势；5口后，迅速下降；在前5口抽吸过程中，烟丝比例及白肋烟比例高的样品逐口释放量较高；第6口，烟丝及白肋烟比例的影响逐渐减弱。（3）烟叶类型、烟丝组成与NNK的逐口释放量（1~6）口间均存在较强的线性回归关系，其复相关系数（R）为0.951 R 0.999，通过适当降低白肋烟比例，增加膨胀烟丝比例可以降低NNK前5口每口释放量。

Analysis of the Impact of Tobacco Structure on Puff-by-puff Release of NNK in Mainstream Smoke

In order to study the relationship between NNK release puff by puff in mainstream cigarette smoke and tobacco structure, we designed and made samples of different types of tobacco and cut tobacco composition. Through the by mouth suction unit linked with RM20H smoking machine, we captured smoke and particulate matter automatically in mainstream smoke, and with reference to national standards, we used HPLC-MS/MS to realize the quantitative analysis of NNK release and trends. The results show that (1) The proportion of tobacco structure had a greater impact on overall NNK release of cigarette, adjusting formula and reducing burley tobacco could effectively reduce the proportion of total releases NNK. (2) NNK's release by mouth with a suction port increased linearly with sequence trend, but the release rapidly declined after the 5th mouth; In the previous 5 pumping process, a high proportion of burley tobacco sample or proportion of normal cut tobacco had a higher release by mouth; At 6th mouth, the influence from proportion of burley and normal cut tobacco gradually declined. (3) There was a strong linear regression relationship among types of tobacco, cut tobacco composition and NNK puff-by-puff release (1~6), the correlation coefficient (R) was range from 0.951 to 0.999, by appropriate reducing the proportion of burley, increasing the proportion of expanded tobacco could reduce the release of NNK puff-by-puff of the previous 5 mouths.