Towards a more rational approach to fungicide design |
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| Affiliation: | 1. USDA-ARS Horticultural Research Laboratory, Fort Pierce, FL, 34945, USA;2. Southern Gardens Citrus Nursery, Clewiston, FL, 33440, USA;1. Department of Seed Science and Technology, CCS Haryana Agricultural University, Hisar 125004, Haryana, India;2. Department of Botany, Maharishi Dayanand University, Rohtak 124001, Haryana, India;3. Department of Vegetable Science, CCS Haryana Agricultural University, Hisar 125004, Haryana, India;4. Department of Genetics and Plant Breeding, CCS Haryana Agricultural University, Hisar 125004, Haryana, India;5. Department of Entomology, CCS Haryana Agricultural University, Hisar 125004, Haryana, India;6. School of Agricultural Sciences, K.R. Mangalam University, Gurugram 122103, India;7. Central Scientific Instruments organisation, Chandigarh 160030, India;1. Universidade Federal do Rio Grande do Norte, Centro de Ciências da Saúde, Departamento de Farmácia, Laboratório de Sistemas Dispersos (LaSiD), Av. Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, 59010-180, Natal, RN, Brazil;2. Institut Galien Paris Sud, CNRS, Univ. Paris-Sud, 92296 Chatenay-Malabry, France;3. Université Paris Sud, Laboratoire de Pharmacognosie, UMR CNRS 8076 BioCIS, Faculté de Pharmacie, 92296 Chatenay-Malabry Cedex, France;1. Microelement Research Center, College of Resources and Environment, Huazhong Agricultural University, Wuhan, Hubei, 430070, PR China;2. Department of Agronomy, University of Agriculture Faisalabad, 38040, Punjab, Pakistan;1. Jiangsu Key Laboratory of Anaerobic Biotechnology, School of Environment and Civil Engineering, Jiangnan University, Wuxi, 214122, P. R. China;2. Center for Separation and Purification Materials & Technologies, Suzhou University of Science and Technology, Suzhou, 215009, P. R. China;1. School of Computing, University of Leeds, Leeds LS2 9JT, UK;2. School of Mathematics and Statistics, UNSW Sydney, NSW 2052, Australia;3. Tilburg University, Tilburg, the Netherlands;4. CWI, INRIA-Erable, Vrije Universiteit, Amsterdam, the Netherlands |
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| Abstract: | Whereas insignificant progress has been made in the chemical control of viruses, mycoplasmas and bacteria, the control of fungal diseases has been significantly improved by the recent introduction of more potent chemicals. However, the shortcomings of these chemicals, the changing background of world agriculture and the decreasing success rate call for more rational approaches in fungicide research. The increasing research efforts in the basic biochemistry of target organisms and host-parasite interactions hold promise for the design of new types of chemicals for plant protection. |
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