Stent angioplasty for treatment of canine valvular pulmonic stenosis |
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| Institution: | 1. Department of Small Animal Clinical Sciences, University of Florida, College of Veterinary Medicine, Gainesville, FL, 32608, USA;2. Congenital Heart Center, 1600 SW Archer Rd, Gainesville, FL, 32610, USA;1. Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Dr., Madison, WI 53706, USA;2. Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Dr., Madison, WI 53706, USA;3. Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Dr., Madison, WI 53706, USA;4. Veterinary Emergency & Referral Group, Brooklyn, NY 11217, USA;1. Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, 200 Westboro Rd, North Grafton, MA 01536, USA;2. Boston Scientific Corporation, 3 Scimed Place, Maple Grove, MN 55311, USA;1. Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA;2. Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L Tharp St., Columbus, OH 43210, USA;3. Department of Clinical Sciences, Colorado State University, 300 W Drake Rd., Fort Collins, CO 80523, USA;1. Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L. Tharp St, Columbus, OH, 43210, USA;2. Department of Medicine, Tulane University School of Medicine, 131 South Robertson Avenue, New Orleans, LA, 70112, USA;3. Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Auburn University, 1220 Wire Road, Auburn, AL, 36849, USA;1. Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L Tharp St., Columbus, OH 43210, USA;2. The Heart Center, Nationwide Children''s Hospital, 700 Children''s Dr., Columbus, OH, 43205, USA |
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| Abstract: | Four dogs presented for evaluation and treatment of severe pulmonic valve stenosis and underwent stenting of the pulmonic valve annulus using bare-metal balloon-expandable stents. All dogs survived the procedure with immediate reduction of the transpulmonary valve pressure gradient and increase in activity levels. One dog had a stent fracture and migration 1 month after the intervention. This dog underwent a second procedure, in which multiple stents were used to alleviate the obstruction. The stents that were placed at the level of the right ventricular outflow tract fractured within 1 month of the procedure, and the patient died when a third (surgical) approach was attempted. The other three dogs remain alive 54, 42, and 29 months after the procedure. Stent angioplasty may be a viable option for dogs with valvular pulmonic stenosis in which routine balloon valvuloplasty does not provide a successful outcome. Aggressive attempts to diminish RVOT dynamic obstruction with high-dose beta blockade and avoiding deployment of the stent within the RVOT are recommended to prevent stent fracture and migration. |
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| Keywords: | Nitinol Dogs Congenital heart disease Valvuloplasty |
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