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Angiotensin-converting enzyme inhibition by Brazilian plants |
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| Authors: | Braga Fernão C Serra Carla P Viana Nilton S Oliveira Alaíde B Côrtes Steyner F Lombardi Júlio A |
| Affiliation: | 1. Faculdade de Farmácia, Universidade Federal de Minas Gerais (UFMG), Av. Antônio Carlos, 6627 CEP 31.270-010, Belo Horizonte, Brazil;2. Escola de Farmácia, Laboratório de Farmacologia Experimental, Universidade Federal de Ouro Preto (UFOP), Ouro Preto, Brazil;3. Departamento de Farmacologia, Instituto de Ciências Biológicas, UFMG, Belo Horizonte, Brazil;4. Departamento de Botânica, Instituto de Ciências Biológicas, UFMG, Belo Horizonte, Brazil |
| Abstract: | The potential antihypertensive activity of Brazilian plants was evaluated in vitro by its ability to inhibit the angiotensin-converting enzyme (ACE). Forty-four plants belonging to 30 families were investigated. Plants were selected based on their popular use as antihypertensive and/or diuretics. The following plants presented significant ACE inhibition rates: Calophyllum brasiliense, Combretum fruticosum, Leea rubra, Phoenix roebelinii and Terminalia catappa. |
| Keywords: | Angiotensin-converting enzyme inhibition Colorimetric assay Brazilian flora |
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