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Evaluation of the in Vitro Anti-Atherogenic Properties of Lipid Fractions of Olive Pomace,Olive Pomace Enriched Fish Feed and Gilthead Sea Bream (Sparus aurata) Fed with Olive Pomace Enriched Fish Feed
Authors:Constantina Nasopoulou  Vassiliki Gogaki  Giorgos Stamatakis  Leonidas Papaharisis  Constantinos A. Demopoulos  Ioannis Zabetakis
Affiliation:1.Laboratory of Food Chemistry, Faculty of Chemistry, School of Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece; E-Mails: (V.G.); (I.Z.);2.Laboratory of Biochemistry, Faculty of Chemistry, School of Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece; E-Mails: (G.S.); (C.A.D.);3.Research and Development Department, Nireus Aquaculture SA, Koropi 19400, Greece; E-Mail:
Abstract:Given the pivotal role of Platelet-Activating-Factor (PAF) in atherosclerosis and the cardio-protective role of PAF-inhibitors derived from olive pomace, the inclusion of olive pomace in fish feed has been studied for gilthead sea bream (Sparus aurata). The aim of the current research was to elucidate the anti-atherogenic properties of specific HPLC lipid fractions obtained from olive pomace, olive pomace enriched fish feed and fish fed with the olive pomace enriched fish feed, by evaluating their in vitro biological activity against washed rabbit platelets. This in vitro study underlines that olive pomace inclusion in fish feed improves the nutritional value of both fish feed and fish possibly by enriching the marine lipid profile of gilthead sea bream (Sparus aurata) with specific bioactive lipid compounds of plant origin.
Keywords:gilthead sea bream (Sparus aurata)   olive pomace   HPLC   platelet activating factor   anti-atherogenic properties
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