| 伊维菌素原粉急性吸入毒性试验研究 |
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| 引用本文： | 胡成云. 伊维菌素原粉急性吸入毒性试验研究[J]. 中国兽药杂志, 2016, 50(4): 48-51 |
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| 作者姓名： | 胡成云 |
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| 作者单位： | 浙江省化工研究院有限公司 |
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| 摘 要： | 对伊维菌素原粉急性吸入毒性进行研究,采用限量试验,设定2000 mg/m3一个剂量组,动式口鼻式染毒,有效染毒时间2 h。结果显示,伊维菌素原粉对雌雄大鼠的急性吸入半数致死浓度(LC50)均大于2089 mg/m3。伊维菌素原粉急性吸入毒性属低毒,该结论为安全使用提供了依据。
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| 关 键 词： | 伊维菌素原粉 急性吸入毒性 半数致死浓度 |
| 收稿时间： | 2016-01-22 |
| 修稿时间： | 2016-02-17 |
Acute Inhalation Toxicity Test of Ivermectin Raw Powder |
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| HU Cheng-yun;LIN Shi-dao;JI Lei;WANG Jian-liang;ZHANG Wu;CEN Jiang-jie. Acute Inhalation Toxicity Test of Ivermectin Raw Powder[J]. Chinese Journal of Veterinary Drug, 2016, 50(4): 48-51 |
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| Authors: | HU Cheng-yun LIN Shi-dao JI Lei WANG Jian-liang ZHANG Wu CEN Jiang-jie |
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| Affiliation: | Zhejiang Research Institute of Industry, LTD. |
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| Abstract: | To study the acute inhalation toxicity of Ivermectin raw powder, provide the basis for safe use. Limit test, the dose group was 2000 mg/m3, dynamic nose-only exposure, effective exposure time for 2 h. The results showed that Ivermectin raw powder in male and female rats acute inhalation median lethal concentration (LC50) were more than 2089 mg/m3. The acute inhalation toxicity was low toxicity. |
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| Keywords: | Ivermectin raw powder acute inhalation toxicity LC50 |
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