中药牛膝中稀土元素含量分析

目的]全面分析牛膝干燥根中的稀土元素含量,为中药牛膝的药效机理研究提供支持。方法]将风干的牛膝根系用粉碎机磨成粉状,应用等离子体质谱仪全面分析牛膝干燥根中的稀土元素含量。结果]牛膝中含有大量的稀土元素,Ce的含量最多,Lu的含量最少。含量超过100 ng/g(DW)的稀土元素有La、Ce和Nd,分别达到158.270、448.698和129.608 ng/g(DW);稀土元素Pr、Sm和Gd的含量均大于20 ng/g(DW);稀土元素Eu、Tb、Dy、Ho、Er、Yb的含量在2.536~14.522 ng/g(DW);稀土元素Tm和Lu的含量低于1 ng/g(DW),分别为0.918和0.848 ng/g(DW)。结论]稀土元素La、Ce和Nd可能在牛膝药效的发挥中起重要作用。

Analysis of the Content of Rare Earth Elements in Chinese Medicine Achytanthes

Objective] The study was to comprehensively analyze the content of rare earth elements in dry root of Achytanthes and provide the support for the study on the pharmacodynamic mechanism of Chinese medicine Achytanthes.Method] The air-drying root of Achytanthes was grinded into the powder by the grinder and the content of rare earth elements in dry root of Achytanthes was comprehensively analyzed through plasma mass spectrometry.Result] Achyranthes contained many rare earth elements.The content of Ce was most and that of Lu was lest.The rare earth elements whose contents were more than 100 ng/g(DW) were La,Ce and Nd,reaching 158.270,448.698 and 129.608 ng/g(DW) resp.The rare earth elements content of Pr,Sm and Gd was more than 20 ng/g(DW),that of Eu,Tb,Dy,Ho,Er,Yb were between 2.536 and 14.522 ng/g(DW) and the rare earth elements contents of Tm and Lu was lower than 1 ng/g·DW,being 0.918 and 0.848 ng/g(DW) resp.Conclusion] The rare earth elements of La,Ce and Nd might have an important role in the efficacy play of Achytanthes.