Hydrodefluorination of perfluoroalkyl groups using silylium-carborane catalysts |
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Authors: | Douvris Christos Ozerov Oleg V |
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Affiliation: | Department of Chemistry, Brandeis University, MS 015, 415 South Street, Waltham, MA 02454, USA. |
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Abstract: | Carbon-fluorine bonds are among the most unreactive functionalities in chemistry. Interest in their activation arises in part from the high global warming potentials of anthropogenic polyfluoroorganic compounds. Conversion to carbon-hydrogen bonds (hydrodefluorination) is the simplest modification of carbon-fluorine bonds, but efficient catalytic hydrodefluorination of perfluoroalkyl groups has been an unmet challenge. We report a class of carborane-supported, highly electrophilic silylium compounds that act as long-lived catalysts for hydrodefluorination of trifluoromethyl and nonafluorobutyl groups by widely accessible silanes under mild conditions. The reactions are completely selective for aliphatic carbon-fluorine bonds in preference to aromatic carbon-fluorine bonds. |
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