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Chemical characterization and biological effects of immature durum wheat in rats
Institution:1. Laboratory of Immunology and Nutrition, Department of Environmental Sciences, Largo dell''Università, Tuscia University, 01100 Viterbo, Italy;2. National Institute for Food and Nutrition Research (INRAN), Rome, Italy;3. Department of Plant Biology and Pathology, Bari University Via E. Orabona 4, I-70125 Bari, Italy;4. Interdisciplinary Center for Biomedical Research (CIR), Università Campus Biomedico di Roma, Via Longoni 83, I-00155 Roma, Italy;5. Experimental Institute of Cerealcoltures, Via Cassia 176, I-00191 Roma, Italy;6. Department of General and Inorganic Chemistry, Analytical Chemistry and Physical Chemistry, Parma University, Parma, Italy;1. Department of Food Science, University of Guelph, Guelph, ON N1G2W1, Canada;2. Agriculture and Agri-Food Canada, Guelph Food Research Centre, Guelph, Ontario N1G 5C9, Canada;3. Department of Plant Agriculture, University of Guelph, Guelph, Ontario N1G 2W1, Canada;4. Agriculture and Agri-Food Canada, Fredericton, New Brunswick E3B 4Z, Canada;5. Faculty of Land and Food Systems, University of British Columbia, Vancouver, BC V6T 1Z4, Canada;1. Regulatory Affairs, Abbott Nutrition, Abbott Laboratories, 3300 Stelzer Road, Columbus, OH 43219, USA;2. MPI Research, Inc., 54943 North Main Street, Mattawan, MI 49071, USA;3. ToxStrategies, Inc., 3260 Blume Drive, Suite 420, Richmond, CA 94806, USA;1. Istituto per i Sistemi Agricoli e Forestali del Mediterraneo, CNR, Sezione di Catania, Str. le V. Lancia, Zona Industriale, Blocco Palma, I 95121 Catania, Italy;2. Centro di Ricerca per le Colture Industriali, CRA, Via di Corticella, 133-40128 Bologna, Italy;1. Department of Food Science and Engineering, Jinan University, Guangzhou 510632, Guangdong, China;2. Agro-food Science and Technology Research Institute, Guangxi Academy of Agricultural Sciences, 174 East Daxue Road, 530007 Nanning, China;3. Guangxi Key Laboratory of Fruits and Vegetables Storage-processing Technology, 174 East Daxue Road, 530007 Nanning, China;4. State Key Laboratory of Food Science and Technology, Synergetic Innovation Center of Food Safety and Nutrition, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu Province 214122, China;5. School of Pharmacy, Health Science Center, Shenzhen University, Shenzhen 518060, China
Abstract:A durum wheat cultivar, Simeto, was grown in experimental fields and samples were collected at various stages of development (from 9 to 45 days after flowering) to assess changes in chemical composition during maturation. Fructans, in particular low molecular weight fructo-oligosaccharides, accumulated in the first 2–3 weeks after anthesis. The cultivar was then grown in an open field and collected at 15 days after anthesis and at maturity 45 days after anthesis. Experimental diets containing 53% wholemeal from immature or mature wheat, were fed for 6 and 12 weeks to two groups of growing rats. Glutathione, vitamins C and E and total hydrophilic or lipophilic antioxidant concentrations were determined in mature and immature wholemeal. The effects of feeding immature and mature wheat diets for the two experimental periods on the immune system, antioxidant status and plasma lipids were studied. Feeding immature wheat increased the proliferation rates of lymphocytes, indicating a stimulating effect on the immune response, decreased the plasma triglycerides and cholesterol levels, indicating a positive effect on lipid profiles. Antioxidant concentrations in blood and lymphocytes did not change significantly.
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