Induction of ovulation in the loach (Paramisgurnus dabryanus) using pimozide and [D-Ala6, Pro9-N-ethylamide]-LHRH |
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| Authors: | Hao-Ren Lin Chun Peng Long-Zhi Lu Xi-Juan Zhou Glen Van Der Kraak R.E. Peter |
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| Affiliation: | 1. Department of Biology, Zhongshan University, Guangzhou China;2. Department of Zoology, University of Alberta, Edmonton, Alta. T6G 2E9 Canada |
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| Abstract: | The effects of intraperitoneal injections of [D-Ala6, Pro9-N-ethylaminde]-luteinizing hormone releasing hormone (LHRH-A) and pimozide (PIM), a dopamine receptor antagonist, on ovulation in loach were investigated. LHRH-A and PIM administered separately were ineffective in inducing ovulation. However, injections of PIM and LHRH-A simultaneously or the injection of PIM 2.5–3 h prior to LHRH-A were highly effective means of inducing ovulation. The simultaneous injection of PIM (1.0 μg/g body wt) and LHRH-A (0.05 μg/g body wt) resulted in a greater ovulatory response than injection of carp pituitary extract (1 pituitary/fish). |
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| Keywords: | To whom correspondence should be addressed |
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