Plasma biochemical responses of the omnivorous crucian carp (<Emphasis Type="Italic">Carassius auratus</Emphasis>) to crude cyanobacterial extracts |
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| Authors: | Xuezhen Zhang Ping Xie Weimin Wang Dapeng Li Zechao Shi |
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| Institution: | (1) Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Fisheries College of Huazhong Agricultural University, Wuhan, 430070, P.R. China;(2) Donghu Experimental Station of Lake Ecosystems, State Key Laboratory of Freshwater Ecology and Biotechnology of China, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, P.R. China;(3) Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Jinzhou, 434000, P.R. China; |
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| Abstract: | Healthy crucian carp (Carassius auratus) were treated by intraperitoneal (i.p.) injection of crude cyanobacterial extracts at two doses, 50 and 200 μg MC-LR equiv kg−1 BW. High mortality (100%) was observed within 60 h post injection in the high-dose group. In the treated fish, activities
of four plasma enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and
lactate dehydrogenase (LDH), all showed substantial increases, with both dose and time-dependent effects. These increases
of enzyme activity indicate severe impairment occurred in the liver of crucian carp over time. Plasma concentrations of energy-related
biomolecules including glucose (GLU), cholesterol (CHO), triglyceride (TG), and total protein (TP) showed marked changes in
the high-dose group, possibly a nutritional imbalance correlated with the liver injury caused by intraperitoneal exposure
to crude cyanobacterial extracts. |
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| Keywords: | Carassius auratus Cyanobacterial extracts Plasma Biochemistry |
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