维药阿育魏实总黄酮抗氧化活性研究 |
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引用本文: | 张慧,章立华,黄琼,热娜·卡斯木.维药阿育魏实总黄酮抗氧化活性研究[J].安徽农业科学,2014(15):4624-4625,4639. |
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作者姓名: | 张慧 章立华 黄琼 热娜·卡斯木 |
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作者单位: | 新疆医科大学药学院; |
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基金项目: | 新疆医科大学创新基金(XJC2011117) |
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摘 要: | 目的]评价阿育魏实总黄酮的抗氧化能力。方法]采用羟自由基、超氧阴离子自由基、亚硝基自由基、DPPH自由基、ABTS自由基体系对阿育魏实总黄酮抗氧化的能力进行研究。结果]在质量浓度0.025~0.500 mg/ml的范围内,阿育魏实总黄酮对羟自由基、超氧阴离子自由基、亚硝基自由基、DPPH自由基、ABTS自由基的清除率分别为31.68%~99.01%、27.45%~90.52%、11.62%~86.40%、41.31%~92.21%和17.53%~62.67%,且存在明显的量效关系。IC50分别为0.038 49、0.053 51、0.271 60、0.026 17和0.033 87 mg/ml。结论]阿育魏实总黄酮具有很好的体外抗氧化活性,是一种新型天然抗氧化物质来源。
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关 键 词: | 阿育魏实 总黄酮 自由基 抗氧化活性 |
Study on Antioxidant Activity of Total Flavonoids of Trachyspermum ammi( L.) Sparuge |
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Institution: | ZHANG Hui, RENA- Kasim et al ( Pharmacy College of Xi'njiang Medical University, Urumqi, Xinjiang 830011 ) |
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Abstract: | Objective] To evaluate antioxidant capacity of total flavonoids of Trachyspermum ammi( L.) Sparuge. Methods]Using hydroxyl free radicals,superoxide anion free radicals,nitroso free radicals,DPPH free radicals,and ABTS free radical system on total flavonoids of Trachyspermum ammi( L.) Sparuge. Results] In the mass concentration within the range of 0. 025-0. 5 mg / ml,its ability to remove the free radicals was 31. 68%-99. 01%,27. 45%-90. 52%,11. 62%-86. 40%,41. 31%-92. 21%,and 17. 53%-62. 67%,and there was significant dose-response relationship. IC50was 0. 038 49 mg / ml,0. 03849 mg / ml,0. 03849 mg / ml,0. 053 51 mg / ml,and 0. 033 87 mg / ml respectively. Conclusion] Total flavonoids of Trachyspermum ammi( L.) Sparuge has high antioxidant activity in vitro and is a new kind of natural antioxidant. |
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Keywords: | Trachyspermum ammi(L ) Sparuge Total flavonoids Free radical Antioxidant activity |
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