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| 猪口蹄疫O型病毒ORMF8测毒试验 | |
| 引用本文： | 郎洪武,王乐元,张永光,王超英,吕红,袁新宇,王家福,魏学峰,李玉和. 猪口蹄疫O型病毒ORMF8测毒试验[J]. 中国兽药杂志, 2004, 38(11): 16-16,15 |
| 作者姓名： | 郎洪武 王乐元 张永光 王超英 吕红 袁新宇 王家福 魏学峰 李玉和 |
| 作者单位： | 1. 中国兽医药品监察所,北京,100081 2. 中国农业科学院兰州兽医研究所,甘肃兰州,730046 3. 中牧股份兰州生物药厂,甘肃兰州,730046 4. 金宇集团内蒙古生物药厂,内蒙古呼和浩特,010030 |
| 摘 要： | 用中国农科院兰州兽医研究所统一提供的猪口蹄疫O型灭活疫苗效检攻毒用种毒ORMF8,在3个企业同时用架子猪进行测毒,分别测得猪的最小感染量(MID)和猪的半数感染量(ID 50).3家单位测得的MID和ID 50分别为10 -6.0 /2 mL,10 -8.2 /2 mL;10 -7.0 /2 mL,10 -7.0 /2 mL;10 -6.0 /2 mL,10 -7.5 /2 mL.将所有实验动物统计计算,MID约为10 -6.3 /2 mL,ID 50约为10 -7.6 /2 mL.从这些数据得出,该试验1 MID约为20 ID 50. |
| 关 键 词： | 猪口蹄疫 O型病毒 测毒 |
| 文章编号： | 1002-1280(2004)11-0016-02 |
Virulence detection of porcine foot and mouth disease virus of ORMF8 in type O |
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| Abstract: | The virulence of foot and mouth disease(FMD) virus of ORMF8 in type O used as the challenge virus when potency tests of porcine FMD vaccine was detected on pigs. The minimal infecting dose(MID) and the (median) infective dose(ID_(50)) were detected by three factories. The MID and ID_(50) determined by Lanzhou Veterinary (Research) Institute, Stock Lanzhou Biological Products Factory and Inner Mongolia Biological Products Factory of Jinyu Group were 10~(-6.0)/2 mL, 10~(-8.2)/2 mL; 10~(-7.0)/2 mL, 10~(-7.0)/2 mL; 10~(-6.0)/2 mL, 10~(-7.5)/2 mL respectively. The statistical results showed MID was 10~(-6.3)/2 mL and ID_(50) was 10~(-7.6)/2 mL. As a result, 1 MID was (equal) to 20 ID_(50) approximately in this test. |
| Keywords: | ORMF8 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |