水产品中邻苯二甲酸酯残留与健康风险评价研究进展

邻苯二甲酸酯（PAEs）是工业上广泛使用的塑料增塑剂，具有神经毒性和生殖发育毒性，能够损伤动物和人的肝脏、肾脏，是一类重要的环境内分泌干扰物质，被列为世界各国“优先污染物”黑名单。饮食是人体暴露于PAEs最主要的途径之一，已在多种食品中检测出PAEs残留。而水产品是人类蛋白质的重要来源，其安全性直接影响消费者的健康。文章从国内外两方面综述了水产品中PAEs污染现状，通过危害鉴定、剂量-反应分析、暴露评价和风险表征等方面论述了通过摄食途径暴露于PAEs的健康风险评价方法，并对今后的研究趋势进行了展望。

Residues of phthalic acid esters in aquatic products and their health risk assessment

Phthalic acid esters （PAEs） are ubiquitous industrial chemicals used as plasticizers in plastics with neural, reproductive and developmental toxicity. As endocrine disrupting agents, they have harsh effects on the liver, kidneys and the reproductive system, so several countries have listed some of PAEs as the priority contaminants. Diet is one of the most important sources through which humans are exposed to PAEs. Residues of PAEs have been detected in various foodstuffs. The safety of aquatic products, which are important in providing proteins for human beings, affect consumers＇ health directly. The review reports on the concentrations and distribution of PAEs in domestic and overseas fishery products, and introduces health risk assessment of human exposure for PAEs via diet through hazard identification, dose-response analysis, exposure assessment and risk characterization. In the end, the research trends are prospected.