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大豆异黄酮的生物活性及毒理学研究进展
引用本文:郭小虎,代晓曼,张波.大豆异黄酮的生物活性及毒理学研究进展[J].大豆科学,2011,30(4):693-696.
作者姓名:郭小虎  代晓曼  张波
作者单位:北京联合大学应用文理学院,生物活性物质与功能食品北京市重点实验室,北京100191
基金项目:国家重点基础研究发展计划(973计划)资助项目(2007CB707805)
摘    要:大豆异黄酮具有预防和治疗妇女更年期综合征、心血管疾病和骨质疏松症等多种生物学活性,并对多种肿瘤如乳腺癌、前列腺癌结肠癌等具有预防和抑制作用.但作为一种重要的植物雌激素,近年来其毒理学作用尤其是对遗传物质以及人类生长发育的影响受到了广泛的关注.文章介绍了大豆异黄酮的重要生物活性并着重综述了大豆异黄酮的毒理学研究进展.

关 键 词:大豆异黄酮  生物活性  毒理学

Advances on the Study of Soybean Isoflavones in Biological Activity and Toxicity
GUO Xiao-hu,DAI Xiao-man,ZHANG Bo.Advances on the Study of Soybean Isoflavones in Biological Activity and Toxicity[J].Soybean Science,2011,30(4):693-696.
Authors:GUO Xiao-hu  DAI Xiao-man  ZHANG Bo
Institution:GUO Xiao-hu,DAI Xiao-man,ZHANG Bo(College of Arts and Sciences,Key Laboratory of Biological Active Materials and Functional Food,Beijing Union University,Beijing 100191)
Abstract:Soy isoflavones have important physiological function in reducing the occurrence of cancer,including mammary cancer,prostate cancer,and colon carcinoma.While as a major phytoestrogen exposed to human,soy isoflavones' genetoxic toxicity especially the growth and development toxicity was widely concerned.The progress on the study of soy isoflavones physiological function especially toxicity were summarized in this paper.
Keywords:Soy isoflavones  Biological activity  Toxicology  
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