A new neuroprotective bakkenolide from the rhizome of Peatasites tatewakianus |
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| Authors: | Sun Zhen-Liang Gao Gang-Long Luo Jian-Ying Zhang Xue-Li Zhang Ming Feng Jing |
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| Institution: | Branch Hospital in Fengxian of Shanghai No 6 People’s Hospital, Shanghai 201400, PR China |
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| Abstract: | Constituents of the fruits of Peatasites tatewakianus were investigated. A new compound, namely bakkenolide-VI (1), was isolated. The structures was elucidated on the basis of 1D, 2D NMR, TOF-MS and ESI-MS techniques, and physicochemical properties. The neuroprotective activity of the new compound was assayed with primary cultured neurons exposed to oxygen-glucose deprivation and oxidative insults. |
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| Keywords: | Peatasites tatewakianus Neuroprotection Bakkenolide-VI |
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