Triterpenes and steroids from the roots of Scorzonera austriaca |
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Authors: | Wu Quan-Xiang Su Yi-Bin Zhu Ying |
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Affiliation: | State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China |
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Abstract: | A new D:B-friedoolean-type triterpene, 3β-acetoxyglutin-5(10)-en-6-oxo (1), together with seventeen known compounds (2-18) was isolated from the roots of Scorzonera austriaca. Their structures were elucidated mainly by NMR and HR-ESI-MS, as well as on comparison with the reported data. Cytotoxicities of compounds 2, 4, 6, 10-14 and 16 against selected cancer cells of human promyelocytic leukemia (HL-60) and human hepatoma (BEL-7404) were measured in vitro. |
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Keywords: | Scorzonera austriaca Asteraceae Triterpenes Steroids 3β-acetoxyglutin-5(10)-en-6-oxo Cytotoxicity |
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