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The effect of aqueous extract of gross and commercial yerba mate (Ilex paraguariensis) on intra-abdominal and epididymal fat and glucose levels in male Wistar rats
Authors:Silva Raquel D'Agostini  Bueno Audrin Loss Scopel  Gallon Carin Weirich  Gomes Luana Ferreira  Kaiser Samuel  Pavei Cabral  Ortega George González  Kucharski Luiz Carlos  Jahn Matheus Parmegiani
Affiliation:
  • a Centro de Ciências da Saúde e Centro de Ciências Agrárias e Biológicas, Universidade de Caxias do Sul (UCS), Av. Francisco Getúlio Vargas, 1130, Caxias do Sul, Rio Grande do Sul, 95070-560, Brazil
  • b Laboratório de Metabolismo e Endocrinologia Comparada, Departamento de Fisiologia, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Sarmento Leite, 500, Porto Alegre, Rio Grande do Sul, 90050-170, Brazil
  • c Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Ipiranga, 2752, Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
  • Abstract:This study analyzed the plasma lipid profile, glucose levels and fat deposits in male rats treated with aqueous extract of gross yerba mate, commercial yerba mate or water. Yerba mate treatment did not change body weight gain and lipid profile. The consumption of gross yerba mate significantly increased blood glucose (6.6 mmol/L) as compared to the water (4.8 mmol/L) and commercial group (5.2 mmol/L) and decreased epididymal and intra-abdominal deposits (10.1 mg/g and 23.7 mg/g of weight) as compared to the water (15.4 mg/g and 36.9 mg/g of weight) and commercial group (12.5 mg/g and 28 mg/g of weight). The results suggest that gross yerba mate reduces fat more efficiently but produces a greater increase in blood glucose when compared to commercial yerba mate and water groups.
    Keywords:VLDL, Very low density lipoprotein   LDL, Low density lipoprotein   HDL, High density lipoprotein   LC, Liquid chromatography   SEM, Standard error of the mean   cAMP, Cyclic adenosine monophosphate   UV, Ultraviolet   MS, Mass spectrometry   CW, Control water   GM, Gross mate   CM, Commercial mate
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