The effect of aqueous extract of gross and commercial yerba mate (Ilex paraguariensis) on intra-abdominal and epididymal fat and glucose levels in male Wistar rats |
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Authors: | Silva Raquel D'Agostini Bueno Audrin Loss Scopel Gallon Carin Weirich Gomes Luana Ferreira Kaiser Samuel Pavei Cabral Ortega George González Kucharski Luiz Carlos Jahn Matheus Parmegiani |
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Affiliation: | a Centro de Ciências da Saúde e Centro de Ciências Agrárias e Biológicas, Universidade de Caxias do Sul (UCS), Av. Francisco Getúlio Vargas, 1130, Caxias do Sul, Rio Grande do Sul, 95070-560, Brazilb Laboratório de Metabolismo e Endocrinologia Comparada, Departamento de Fisiologia, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Sarmento Leite, 500, Porto Alegre, Rio Grande do Sul, 90050-170, Brazilc Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Ipiranga, 2752, Porto Alegre, Rio Grande do Sul, 90610-000, Brazil |
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Abstract: | This study analyzed the plasma lipid profile, glucose levels and fat deposits in male rats treated with aqueous extract of gross yerba mate, commercial yerba mate or water. Yerba mate treatment did not change body weight gain and lipid profile. The consumption of gross yerba mate significantly increased blood glucose (6.6 mmol/L) as compared to the water (4.8 mmol/L) and commercial group (5.2 mmol/L) and decreased epididymal and intra-abdominal deposits (10.1 mg/g and 23.7 mg/g of weight) as compared to the water (15.4 mg/g and 36.9 mg/g of weight) and commercial group (12.5 mg/g and 28 mg/g of weight). The results suggest that gross yerba mate reduces fat more efficiently but produces a greater increase in blood glucose when compared to commercial yerba mate and water groups. |
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Keywords: | VLDL, Very low density lipoprotein LDL, Low density lipoprotein HDL, High density lipoprotein LC, Liquid chromatography SEM, Standard error of the mean cAMP, Cyclic adenosine monophosphate UV, Ultraviolet MS, Mass spectrometry CW, Control water GM, Gross mate CM, Commercial mate |
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