| 肥大细胞在机体防御反应中的作用 |
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| 引用本文： | 孙泉,佘锐萍,王德成,刘天龙,张艳梅,罗冬梅,王英华. 肥大细胞在机体防御反应中的作用[J]. 动物医学进展, 2007, 28(8): 83-86 |
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| 作者姓名： | 孙泉 佘锐萍 王德成 刘天龙 张艳梅 罗冬梅 王英华 |
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| 作者单位： | 中国农业大学动物医学院,北京,100094;中国农业大学动物医学院,北京,100094;中国农业大学动物医学院,北京,100094;中国农业大学动物医学院,北京,100094;中国农业大学动物医学院,北京,100094;中国农业大学动物医学院,北京,100094;中国农业大学动物医学院,北京,100094 |
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| 摘 要： | 肥大细胞的研究主要集中在过敏性痰病中,肥大细胞在机体抵御病原体感染中发挥着重要作用.肥大细胞除具有识别、吞噬并杀灭病原微生物的功能外,尚能加工、递呈抗原和调节免疫反应.肥大细胞有针对病原信号的特异性受体系统和介质.深入阐明肥大细胞在细菌和病毒感染中的作用和机制,不仅为天然免疫的研究开辟一个新领域,而且对感染性疾病的防治也有重要意义.
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| 关 键 词： | 肥大细胞 宿主防御 细菌感染 病毒感染 |
| 文章编号： | 1007-5038（2007）08-0083-04 |
| 修稿时间： | 2007-05-08 |
The Role of Mast Cells in Host Defence |
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| SUN Quan,SHE Rui-ping,WANG De-cheng,LIU Tian-long,ZHANG Yan-mei,LUO Dong-mei,WANG Ying-hua. The Role of Mast Cells in Host Defence[J]. Progress In Veterinary Medicine, 2007, 28(8): 83-86 |
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| Authors: | SUN Quan SHE Rui-ping WANG De-cheng LIU Tian-long ZHANG Yan-mei LUO Dong-mei WANG Ying-hua |
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| Affiliation: | College of Veterinary Medicine,China Agricultural University,Beijing,100094,China |
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| Abstract: | More attentions have been paid on the role of mast cells in allergic diseases,however,the importance of mast cells against several pathogens in host defence has been revealed.Mast cells not only have the ability to recognize and phagocytize pathogens,then kill them,but they can also present antigens and regulate immunity response.There are special receptors and mediators of mast cells in response to pathogens.To illuminate the mechanism by which mast cells play in bacterial and viral infections not only develops a new territory for the innate immunity,but also plays a crucial role in the prevention and cure of infectious diseases. |
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| Keywords: | mast cells host defence bacterical infection viral infection |
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