| 兔出血症病毒人工感染幼兔的病理学研究 |
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| 引用本文： | 黄吉风,徐福南.兔出血症病毒人工感染幼兔的病理学研究[J].南京农业大学学报,1997,20(2):77-81. |
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| 作者姓名： | 黄吉风 徐福南 |
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| 作者单位： | 南京农业大学动物医学院 |
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| 摘 要： | 用兔出血症病毒（ＲＨＤＶ）分别感染５，１５和２５日龄家兔，接种后７２ｈ扑杀，对其肝，脾，肺，肾，胸腺，骨髓等作组织病理学和超微结构观察，发现幼兔感染ＲＨＤＶ与成年兔病毒性出血症不同，其主要病变是血管内皮细胞，网状细胞的增生和肝，肾等脏器实质细胞的变性，ＲＨＤＶ对一月龄以内幼兔抗亦具有感染性，并对其肝，肾等造成一定程度的病理损伤，病理损伤程度随年龄的增长而加重。
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| 关 键 词： | 幼兔 出血症病毒 病理学 |
PATHOLOGICAL STUDIES ON EXPERIMENTAL INFECTIONS OF RABBIT HAEMORRHAGIC DISEASE VIRUS (RHDV) IN SUCKLING RABBITS |
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| Huang Jifeng and Xu Funan.PATHOLOGICAL STUDIES ON EXPERIMENTAL INFECTIONS OF RABBIT HAEMORRHAGIC DISEASE VIRUS (RHDV) IN SUCKLING RABBITS[J].Journal of Nanjing Agricultural University,1997,20(2):77-81. |
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| Authors: | Huang Jifeng and Xu Funan |
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| Abstract: | Suckling rabbits (5,15 and 25 days old) experimentally infected by RHDV were killed at 72 h post infection. Histopathological and ultrastructural changes of liver, spleen, lung, kidney, thymus and bone marrow were examined. The results showed that the characteristic fetures of RHD pathological lesions, such as extensive haemorrhages and disseminated intravascular coagulation (DIC), were not observed. Proliferations of the endothelial cells of blood vessels and reticular cells, degenerations of hepatocytes and epithelial cells of nephron tubules were the characteristic alterations. The results suggested that RHDV could infect suckling rabbits and produce some lesion in liver and kidney, older the animal, more severe the lesion. |
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| Keywords: | suckling rabbits rabbit haemorrhagic disease pathology |
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