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参芍洁阴洗液最佳提取工艺研究
引用本文:张金萍,毛丽超,王诗惠,张薇,刘京硕,金向群,尹万坤. 参芍洁阴洗液最佳提取工艺研究[J]. 特产研究, 2012, 0(1): 44-46
作者姓名:张金萍  毛丽超  王诗惠  张薇  刘京硕  金向群  尹万坤
作者单位:吉林大学药学院;长春远大国奥制药有限公司
摘    要:优选参芍洁阴洗液的最佳提取工艺。采用正交试验方法,以苦参碱和氧化苦参碱总含量为指标,筛选参芍洁阴洗液最佳提取工艺条件。参芍洁阴洗液最佳提取工艺条件为水煮液密度1.12g/mL(20℃),醇沉百分数60%,pH=8。优选得到的工艺稳定可行,能显著提高苦参碱和氧化苦参碱的含量。

关 键 词:参芍洁阴洗液  苦参碱  氧化苦参碱  正交试验  提取工艺

Optimization of Extraction Technology of Shen Shao Jie-Yin lotion
ZHANG Jin-ping,MAO Li-chao,WANG Shi-hui,ZHANG Wei,LIU Jing-shuo,JIN Xiang-qun,YIN Wan-kun. Optimization of Extraction Technology of Shen Shao Jie-Yin lotion[J]. Special Wild Economic Animal and Plant Research, 2012, 0(1): 44-46
Authors:ZHANG Jin-ping  MAO Li-chao  WANG Shi-hui  ZHANG Wei  LIU Jing-shuo  JIN Xiang-qun  YIN Wan-kun
Affiliation:1.Scohool of Pharmaceutical Sciences of Jilin University,Changchun 130012,China; 2.Yuan Da Guo Ao Pharmacy Co.,Ltd.Changchun,Changchun 130012,China)
Abstract:To confirm the optimization extraction way of the shenshao jie-yin lotion,an orthogonal test was adopted in this study,and the total contents of matrine and oxymatrine were used as sensitive indicator.The best purification conditions of the shenshao jie-yin lotion were as follows: concentrated boiling liquid density was 1.12g/mL(20℃),precipitated rate of alcohol was 60%,and pH value was 8.The optimum process was stable,feasible and can significantly increase the content of matrine and oxymatrine.
Keywords:Shenshao jie-yin lotion  Matrine  Oxymatrine  Orthogonal test  Purification technology
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