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QFM合剂麻醉剂量对犬肝、肾功能的影响
引用本文:刘焕奇,王洪斌,侯振中,霍慧君,王林安.QFM合剂麻醉剂量对犬肝、肾功能的影响[J].中国兽医学报,2003,23(4):380-382.
作者姓名:刘焕奇  王洪斌  侯振中  霍慧君  王林安
作者单位:东北农业大学,动物医学院,黑龙江,哈尔滨,150030
基金项目:黑龙江省青年科学基金资助项目(Q95B07)
摘    要:QFM合剂是一种新型的犬用复合麻醉制剂。本试验旨在研究其对犬肝、肾功能的影响。试验用7条犬肌肉注射QFM合剂0.15~0.2mL(每千克体质量),观察比较了注药前、后犬血清GOT、GPT、AKP活性和尿素氮、肌酐含量的变化。结果证明:注药前、后犬血清GOT、GPT、AKP活性和尿素氮、肌酐含量的变化差异不显著,在正常生理范围内。说明QFM合剂应用于犬的麻醉,时犬的肝、肾功能无明显不良影响,进一步证明了QFM合剂应用于犬的临床安全性。

关 键 词:QFM合剂  麻醉  剂量    肝功能  肾功能  复合麻醉剂  临床安全性
文章编号:1005-4545(2003)04-0380-02
修稿时间:2002年6月11日

Influence of QFM Combination on the Function of Liver in Dogs at Anaesthetic Dose
LIU Huan qi,WANG Hong bin ,HOU Zhen zhong,HUO Hui jun,WANG Lin an.Influence of QFM Combination on the Function of Liver in Dogs at Anaesthetic Dose[J].Chinese Journal of Veterinary Science,2003,23(4):380-382.
Authors:LIU Huan qi  WANG Hong bin  HOU Zhen zhong  HUO Hui jun  WANG Lin an
Institution:LIU Huan qi,WANG Hong bin *,HOU Zhen zhong,HUO Hui jun,WANG Lin an
Abstract:QFM combination is a new compound anaesthetic agent for dog.The influence of QFM combination on the function of liver and kidney in dogs at anaesthetic dose was studied in this experiment.QFM combination was administrated at the dose of 0 15 0 2 mL/kg body weight intramuscularly in 7 dogs.Activity of GOT,GPT,AKP and the concentration of creatinine and BUN in serum were determined before and after QFM combination being administrated.The result showed that:variation of activity of GOT,GPT,AKP and the concentration of creatinine and BUN in serum was not significant(P>0 05) and within the physiological range.This indicates that QFM combination has no obvious bad effects on the function of liver and kidney of dogs when administrated at anaesthetic dose,and that QFM combination is safe in clinical application.
Keywords:QFM combination  dog  liver  kidney
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