首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Bone marrow hypoplasia and intestinal crypt cell necrosis associated with fenbendazole administration in five painted storks
Authors:Weber Martha A  Terrell Scott P  Neiffer Donald L  Miller Michele A  Mangold Barbara J
Institution:Disney's Animal Kingdom, Lake Buena Vista, FL 32830, USA.
Abstract:Five painted storks were treated with fenbendazole for 5 days for internal parasitism. Four birds died following treatment. Profound heteropenia was a consistent finding in all samples evaluated; additionally, the 1 surviving bird had progressive anemia. Consistent necropsy findings in the 4 birds that died were small intestinal crypt cell necrosis and severe bone marrow depletion and necrosis. Fenbendazole has been associated with bone marrow hypoplasia and enteric damage in mammals and other species of birds. The dosages of fenbendazole used in birds are often substantially higher than those recommended for mammals, which may contribute to bone marrow hypoplasia and intestinal crypt cell necrosis associated with fenbendazole administration in birds.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号