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阿米卡星脂质体对猪肺疫的疗效试验
引用本文:陈小军,陶志瑛,孙志良,刘进辉,刘伟,王慧,胡卫平.阿米卡星脂质体对猪肺疫的疗效试验[J].动物医学进展,2008,29(10).
作者姓名:陈小军  陶志瑛  孙志良  刘进辉  刘伟  王慧  胡卫平
作者单位:1. 湖南农业大学动物医学院,湖南,长沙,410128
2. 湖南岳阳市动物防疫监督站,湖南,岳阳,414000
3. 湖南农业大学动物医学院,湖南,长沙,410128;湖南五指峰药业生化有限公司,湖南,浏阳,411216
4. 湖南五指峰药业生化有限公司,湖南,浏阳,411216
摘    要:为研究阿米卡星脂质体的临床疗效,对10例被诊断为患猪肺疫(猪巴氏杆菌病)的仔猪进行了疗效试验。将患猪随机分为3组,空白对照组肌肉注射生理盐水;药物对照组肌肉注射阿米卡星,剂量为7.5mg/kg,每天用药2次,连用5d;试验药物组肌注阿米卡星脂质体,剂量为5.0mg/kg,每天用药1次,连用3d。结果表明,阿米卡星脂质体组治愈率和有效率分别为70.0%和76.0%,疗效显著高于药物对照组(P〈0.01)。

关 键 词:阿米卡星脂质体  猪肺疫  疗效

Curative Test of Liposomal Amikacin on Pasteurellosis in Pigs
CHEN Xiao-jun,TAO Zhi-ying,SUN Zhi-liang,LIU Jin-hui,LIU Wei,WANG Hui,HU Wei-ping.Curative Test of Liposomal Amikacin on Pasteurellosis in Pigs[J].Progress In Veterinary Medicine,2008,29(10).
Authors:CHEN Xiao-jun  TAO Zhi-ying  SUN Zhi-liang  LIU Jin-hui  LIU Wei  WANG Hui  HU Wei-ping
Institution:1.College of Veterinary Medicine;Hunan Agricultural University;Changsha;Hunan;410128;China;2.Hunan Yueyang Epidemic Prevention and Inspection Station;Yueyang;414000;3.Hunan Wuzhifeng Biochemistry CO.;LTD;Liuyang;411216;China
Abstract:110 pigs infected with Pasteurella multocida were tested in order to study curative effect of liposomal amikacin.The pigs were divided into 3 groups.The pigs in blank control group were administered with physiological saline,the pigs in drug control group were administered with amikacin for 5 days(7.5 mg/kg,2 times a day),and the pigs in test group were administered with liposomal amikacin for 3 days(5.0 mg/kg,once a day).The administration ways were all muscular injection.The results showed that the cure r...
Keywords:liposomal amikacin  pig pasteurellosis  curative effect  
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