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鸡传染性法氏囊病的组织病理学及超微结构变化的研究
引用本文:徐福南,金玲,吴颖.鸡传染性法氏囊病的组织病理学及超微结构变化的研究[J].南京农业大学学报,1987(2).
作者姓名:徐福南  金玲  吴颖
作者单位:南京农业大学兽医病理教研组 (徐福南,金玲),江阴县兽医站(吴颖)
摘    要:本研究采用40日龄自然感染传染性法氏囊病病鸡20只,进行了组织病理学和超微结构检查。组织病理学变化包括法氏囊、脾和胸腺的淋巴细胞坏死,坏死部位有异嗜性白细胞浸润以及巨噬细胞和网状细胞增生、滤泡之间水肿、肾病及病毒性脑脊髓炎等。超微结构变化的特征是淋巴样组织坏死,表现为电子密度增加,核的染色质边移。网状细胞和巨噬细胞出现很多约55nm的呈结晶状排列、周围无囊膜的病毒颗粒,有些自噬空泡中也含有病毒颗粒。肾远曲小管的微绒毛丧失或数目减少,核浓缩或溶解,靠近肾小管管腔的细胞浆中有很多自噬空泡。

关 键 词:超微结构    法氏囊病

STUDIES ON HISTOPATHOLOGY AND ULTRASTRUCTURE OF INFECTIOUS BURSAL DISEASE(IBD)IN CHICKEN
Xu Funan and Jing Lin.STUDIES ON HISTOPATHOLOGY AND ULTRASTRUCTURE OF INFECTIOUS BURSAL DISEASE(IBD)IN CHICKEN[J].Journal of Nanjing Agricultural University,1987(2).
Authors:Xu Funan and Jing Lin
Abstract:Examination of histopathology and ultrastructure in IBD of 20 chickens aged 40 days was carried out. Histopathoiogical changes included necrosis of lymphocytes in bursae of Fabricius, spleen and thymus, infiltration by heterphils, macrophages and recticular ceils and interfollicular edema, nephropathy and virul encephalomyelitis. Ultrastructural changes were characterized by the necrosis in lymphoid tissue. Numerous virus particles about 55nm in size, arrayed in a crystalline pattern and not surrounded by membrane appeared in reticular cells, macrophages and some autophagic vacuoles containing virus, and they were characterized by the losses and reduced number of microvilli of distal convoluted tubules, pyknosis, karyolysis of nucleus and many autophagic vacuoles near the lumen on the kidney.
Keywords:Ultrastructure  Chicken  Bursal disease  
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