Comparative efficacy of bromocriptine,cabergoline and thyroxine in inducing oestrus in bitches |
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Authors: | G Ajitkumar T Sreekumaran R Praseeda K A Mercy K N Aravinda Ghosh |
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Institution: | (1) Department of Animal Reproduction, Gynaecology and Obstetrics, College of Veterinary and Animal Sciences, Kerala Agricultural University, Mannuthy, Thrissur, Kerala, India, 680 651 |
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Abstract: | Forty bitches in anoestrus for more than six months from the last heat, with a serum progesterone level less than 1 ng/ml
were subjected to oestrus induction trials using anti-prolactin drugs and levothyroxine, once daily orally for 20 consecutive
days. The mean serum progesterone level among them was found to be 0.57 ± 0.03 ng/ml. Out of 10 animals treated in each group,
five (50%) in Group I (bromocriptine @ 50 μg/kg body weight), nine (90%) in Group II (cabergoline @ 5 μg/kg body weight),
eight (80%) in Group III (thyroxine @10 μg/kg body weight) and seven (70%) in Group IV (thyroxine @ 5 μg/kg body weight) responded
by evincing proestrual bleeding. The mean (±SEM) time taken from initiation of treatment to onset of proestrual bleeding in
Groups I, II, III and IV was 28 ± 3.39, 13.44 ± 3.12 (P < 0.05), 24.50 ± 3.18 and 33 ± 2.21 days respectively. The mean (±SEM)
duration of proestrus and oestrus in the treatment groups was 9.80 ± 0.86, 10.11 ± 0.68, 11.25 ± 0.88 and 10.71 ± 0.68 days
and 7.60 ± 0.24, 8 ± 0.29, 8.5 ± 0.63 and 7.85 ± 0.46 days respectively. The conception rate in relation to the number of
animals responding to oestrus induction in the treatment groups was 80%, 78%, 63% and 57%, respectively. The mean (±SEM) gestation
length calculated from the last breeding date and litter size in the treatment groups varied from 60.50 ± 1.55 to 64.00 ± 0.82 days
and 5.14 ± 0.34 to 6.40 ± 0.40 respectively. |
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