| 长效恩诺沙星注射液在健康猪体内的药动学 |
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| 引用本文： | 周云波,吴海燕,鞠晓峰,郭艳清,完善春,陈志宝. 长效恩诺沙星注射液在健康猪体内的药动学[J]. 黑龙江八一农垦大学学报, 2005, 17(3): 70-72 |
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| 作者姓名： | 周云波 吴海燕 鞠晓峰 郭艳清 完善春 陈志宝 |
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| 作者单位： | 黑龙江省泰来县泰来镇畜牧站,泰来镇,162400;黑龙江八一农垦大学;鸡东县畜牧局;鸡西市畜牧局 |
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| 摘 要： | 为了解长效恩诺沙星在健康猪体内的药动力学,进行了本研究。应用HPLC法测定血浆药物浓度,所得数据用MCPKP药代力学软件处理。实验结果表明,长效恩诺沙星注射剂药物半衰期明显延长,差异显著性P<0.01,生物利用度有所提高。
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| 关 键 词： | 恩诺沙星 药动学 HPLC 猪 |
| 文章编号： | 1002-2090(2005)03-0070-03 |
Pharmacokinetics of Enroofloxacin in Healthy Pig |
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| ZHOU Yun-bo,WU Hai-yan,JU Xiao-feng et al.. Pharmacokinetics of Enroofloxacin in Healthy Pig[J]. journal of heilongjiang bayi agricultural university, 2005, 17(3): 70-72 |
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| Authors: | ZHOU Yun-bo WU Hai-yan JU Xiao-feng et al. |
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| Abstract: | To make sure the pharmacokinetic characterisrics of enrofloxacin inuhealthy pig were studied. The concentrations of enrofloxacin and its metabolite were determined by a high performance liquid chromatography (HPLC).The c-t data of enrofloxacin in plasm were analysed with MCPKP program. The results showed that the elimination half life could prolong significantly and P<0.01. |
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| Keywords: | enrofloxacin pharm acok inetics HPLC swine |
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