Respiratory disease in neonatal cloned calves |
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Authors: | Brisville A C Fecteau G Boysen S Dorval P Buczinski S Blondin P Smith L C |
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Institution: | Hopital des animaux de la Ferme, Centre Hospitalier Universitaire Vétérinaire, Faculté de Médecine Vété, Université de Montréal, Saint-Hyacinthe, QC, Canada. anne-claire.brisville@umontreal.ca |
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Abstract: | Background: Numerous clinical abnormalities occur in cloned calves during the neonatal period. Objectives: Describe respiratory diseases affecting cloned calves. Animals: Twenty‐five cloned Holstein calves. Methods: Retrospective clinical study of the cloned calves born at the Veterinary Teaching Hospital, Saint‐Hyacinthe, QC. Results: Records of 31 cloned calves were reviewed. Twenty‐five records were included. Four stillborn calves and 2 calves euthanized at birth were excluded. Twenty‐two calves suffered from respiratory diseases. Nineteen calves received intranasal oxygen treatment (INO). They were tachypneic (78 breaths per minute) and 5 of them were hypoxemic (PaO2 < 55 mmHg). Two of 19 calves remained hypoxemic despite INO. Thirteen calves were weaned from INO after a median of 70 hours and were discharged at a median of 5 days of age. Nine calves required ventilatory support: 3 from birth and 6 after INO. Five were successfully weaned from the ventilator after a median of 32 hours and were discharged at a median of 8 days of age. Three calves died and 1 was euthanized because of respiratory disease. Necropsy revealed atelectasis, pulmonary congestion, and alveolar damages. Conclusion and Clinical Importance: Respiratory disease occurs frequently in cloned calves. The most frequent abnormality is hypoxemia because of V/Q mismatch. It is possible to successfully support these calves by INO and mechanical ventilation. |
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Keywords: | Blood gas analysis Hypoxemia Intranasal oxygen Mechanical ventilation V/Q mismatch |
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