“创伤愈合药”喷雾剂制备及其对创伤治疗作用的研究

为研制“创伤愈合药”喷雾剂并进行初步药效学实验。选择最优工艺制备“创伤愈合药”喷雾剂，对其有效成分血竭素进行定性鉴别和含量测定作为质量控制，采用实验性创伤模型考察喷雾剂的治疗作用。结果表明：制剂中血竭素的平均含量是0.01902 mg，符合制定的质量标准；“创伤愈合药”喷雾剂对家兔创伤在第5天和第10天的结痂率分别为96.09%、99.68%，治愈率分别为62.86%、99.50%。表明：其具有杀菌镇痛，收敛生肌的作用，有效防止了细菌感染和缩短了创伤愈合时间。“创伤愈合药”喷雾剂工艺合理，质量可控，对创伤具有治疗作用。

The Preparation and Trauma Treatment Function Study of the “Wound Healing Medicine” Spray

In order to triturate the ＂Wound Healing Medicine＂ spray and conducting the primary pharmaco dynamical experiment. Selecting the optimal process to the preparation of the ＂Wound Healing Medicine＂ spray, the qualitative discrimination and the content determination of its active ingredient-dracorhodin were the quality controls, it adopted the experimental trauma model to investigate the treatment function of this spray. The results showed that in preparations, the average content of dracorhod in was 0.01902 mg which in line with established quality standards; ＂Wound Healing Medicine＂ spray, the crusted rate of rabbit wounds were 96.09%, 99.68% and cure rates were 62.86%, 99.50% at 5 days and 10 days after treatment, The results indicated that the spray had sterilization, analgesia, promote tissue regeneration, and prevent the bacterial infections and shorten the wound healing time effectively. The process of the ＂Wound Healing Medicine＂ spray was rational, quality controlled, and had the therapeutic action to wound.