左旋咪唑防治奶牛隐性乳房炎的使用方法

选择患隐性乳房炎的中国荷斯坦奶牛95头（条件相当），随机将其分为19个组，即左旋咪唑口服刺型，7．5mg／kg1次组、7．5mg／kg1次剂量并间隔10d重复1次组、7．5mg／kg1次剂量并间隔20d重复1次组、10．0mg／kg1次组、10．0mg／kg1次剂量并间隔10d重复1次组、10．0mg／kg1次剂量并间隔20d重复1次组、12．5mg／kg1次组、12．5mg／kg1次剂量并间隔10d重复1次组、12．5mg／kg1次剂量并间隔20d重复1次组；左旋咪唑注射剂型。5．0mg／kg1次组、5．0mg／kg1次刺量并间隔10d重复1次组、5．0mg／kg1次剂量并间隔20d重复1次组、7．5mg／kg1次组、7．5mg／kg1次剂量并间隔10d重复1次组、7．5mg／kg1次剂量并间隔20d重复1次组、10．0mg／kg1次组、10．0mg／kg1次剂量并间隔10d重复1次组、10．0mg／kg1次剂量并间隔20d重复1次组，1个对照组不用药。试验前和用药后每间隔10d用BMT法检测各头奶牛的隐性乳房炎情况，对其检测结果打分，每组以其加权平均值考核，试验结果表明，口服剂型以7．5mg／kg1次剂量并间隔10d重复1次组和注射剂型以5．0mg／kg1次剂量并间隔10d重复1次组的效果较好，这2种应用方法比较以7．5mg／kg1次剂量并间隔10d重复1次的方法最佳。然后田间试验，选择条件相当的2群奶牛。一群（55头）应用左旋咪唑7．5mg／kg1次剂量并间隔10d重复1次的方法防治隐性乳房炎，另一群（53头）为不用药对照，结果隐性乳房炎恢复率、转化成临床型乳房炎奶牛数量和产奶牛量，用药牛群均好于不用药牛群。

Prevention and Treatment Technique for Latent Mastitis of Dairy Cattle Using Levamisole

In order to explore a preferable method for prevention and treatment of the latent mastitis in dairy cattle using laevo-rotatary imidasole,95 Chinese Holstein dairy cows with latent mastitis were divided into 19 groups. Among them,the 18 groups were treated with the dosage of 5.0 mg/kg once,5.0 mg/kg twice at interval of 10 d and 20 d by IM;7.5 mg/kg once, 7.5 mg/kg twice at interval of 10 d and 20 d,10.0 mg/kg once,10.0 mg/kg twice at interval of 10 d and 20 d,12.5 mg/kg once and 12.5 mg/kg twice at interval of 10 d and 20 d per os,respectively. The another was not treated as control group. The BMT was used to diagnose the latent mastitis per 10 d for 90 days. The results showed that the dosage of 5.0 mg/kg twice at interval of 10 d by IM and the dosage of 7.5 mg/kg twice at interval of 10 d per os were the best among them and the latter was much better than the former. Furthermore,in the field trails a group of 55 cows was prevented with the latter method and another group of 55 cows not treated as control. The result also showed the oral administration of the levamisole was effective ,reliable and feasible for the prevention and treatment of the latent mastitis in dairy cow.