| 硫酸头孢喹肟注射液的制备工艺研究 |
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| 引用本文： | 宋永军,李向阳,朱华伟,付旭东. 硫酸头孢喹肟注射液的制备工艺研究[J]. 中国动物保健, 2014, 0(5): 11-14 |
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| 作者姓名： | 宋永军 李向阳 朱华伟 付旭东 |
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| 作者单位： | [1]普莱柯生物工程股份有限公州,河南洛阳471000 [2]国家兽用药品工程技术研究中心,河南洛阳471003 [3]洛阳惠中兽药有限公司,河南洛阳471013 [4]石家庄动物疾病预防控制中心,河北石家庄050000 |
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| 摘 要： | 通过对硫酸头孢喹肟注射液的辅料及分散工艺进行研究，确定了硫酸头孢喹肟注射液的制备工艺。选择油酸乙酯为载体并对其相容性进行了研究；确定了2．0％的硬脂酸铝作为助悬剂；确定了1．0％的卵磷脂作为表面活性剂；确定了高剪切分散后过高压均质机均质作为分散工艺，最终确定了硫酸头孢喹肟注射液的制备工艺。并将产品按照质量标准进行检测，结果符合规定。
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| 关 键 词： | 硫酸头孢喹肟 制备工艺 |
Study on Cefquinome Sulfate Injection Preparation Process |
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| Song Yongjun,Li Xiangyang,Zhu Huawei,Fu Xudong. Study on Cefquinome Sulfate Injection Preparation Process[J]. China Animal Health, 2014, 0(5): 11-14 |
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| Authors: | Song Yongjun Li Xiangyang Zhu Huawei Fu Xudong |
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| Affiliation: | 1.Pulike Biological Engineering Co., Ltd. Luoyang Henan, 471000; 2.National Engineering Research Center for Velerinary Medicine, Luoyang Henan, 471003;3.Luoyang Huizhong veterinary Ltd. Luyang Henan, 471013;4.Animal Disease Control and Prevention Center of Shijiazhuang, Shijiazhuang Hebei. 050000) |
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| Abstract: | According to the study of materials and dispersion process to cefquinome sulfate injection,the prepa- ration of cefquinome sulfate injection is identified. Oleate is selected as a carrier and its compatihility is studied, 2.0% aluminum stearate as a suspending agent, 1.0% lecithin is determined as a surface active agent, ilomogenizing by high-pressure homogenizer after high shear dispersion as the dispersion process. Eventually, the preparation process to eefquinome sulfate injection determined and product quality conform to standard. |
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| Keywords: | cefquinome sulfate preparation process |
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