Evaluation of biological activities of extracts from 22 African tropical wood species |
| |
Authors: | Zeen Huang Koh Hashida Rei Makino Fumio Kawamura Kuniyoshi Shimizu Ryuichiro Kondo Seiji Ohara |
| |
Affiliation: | (1) Faculty of Forestry, University of Toronto, 33 Willcocks Street, Toronto, Ontario, M5S 3B3, Canada;(2) Department of Biomass Chemistry, Forestry and Forest Products Research Institute, Tsukuba, Ibaraki 305-8687, Japan;(3) Forestry Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305-8686, Japan;(4) Systematic Forest and Forest Products, Faculty of Agriculture, Kyushu University, Fukuoka 812-8581, Japan |
| |
Abstract: | Heartwoods of 22 African tropical wood species were extracted with methanol and the contents of total phenolic compounds in these extracts were measured. Three bioassays were conducted to evaluate the antioxidant activity, tyrosinase inhibitory activity, and antifungal activity of the methanol extracts. The results indicated that the extracts from 13 species exhibited high antioxidant potential, and their inhibitory concentrations that caused 50% scavenging of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (IC50) were less than 10 μg/ml. The crude extract from Cylicodiscus gabunensis showed the highest antioxidant activity, and was even higher than that of (+)-catechin, which is known as a potent antioxidant. There was a good correlation between the antioxidant activity and the content of total phenolic compounds, indicating that phenolic compounds played a predominant role in the antioxidant property of the wood extracts. Among all 22 species, only 1 species, Milicia excelsa, contained extractives that showed very high tyrosinase inhibitory activity. The extracts from 9 species showed high antifungal activity. No consistent relationship was observed between the tyrosinase inhibitory activity or antifungal activity and the content of total phenolics in the extracts. Part of this article was presented at the 56th Annual Meeting of the Japan Wood Research Society, Akita, August 2006 |
| |
Keywords: | Antioxidant activity Tyrosinase inhibitory activity Antifungal activity African tropical wood species Total phenolic compounds |
本文献已被 SpringerLink 等数据库收录! |
|