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| 鸡传染性法氏囊病病毒地方流行毒株的免疫原性 | |
| 引用本文： | 马增军,芮萍,李佩国,刘华格,崔学文,张志全,董淑珍.鸡传染性法氏囊病病毒地方流行毒株的免疫原性[J].中国兽医学报,2007,27(2):164-167. |
| 作者姓名： | 马增军 芮萍 李佩国 刘华格 崔学文 张志全 董淑珍 |
| 作者单位： | 1. 河北科技师范学院,动物科技系,河北,秦皇岛,066600 2. 河北省畜牧局,河北,石家庄,050011 3. 河北省迁安市职教中心,河北,迁安,064400 |
| 摘 要： | 从河北省一些发病鸡场分离到JD1～JD10共10株鸡传染性法氏囊病病毒(IBDV)毒株,用IBD标准阳性血清以琼扩试验进行了初步鉴定.并进行了IBDV分离物及其鸡胚适应毒免疫原对标准强毒IBDV-BC6/85株免疫保护试验,D78弱毒疫苗对IBDV各分离毒株的免疫保护试验以及分离毒株间交互免疫保护试验.结果表明,D78疫苗对JD2,JD5和JD10 IBDV分离株的保护率较低,分别为40%、50%和60%.分离毒株JD5、JD2及其鸡胚传代物E-JD2对强毒株的免疫保护率可达100%.交互免疫保护试验表明,JD2对其余各分离株的免疫保护指数达到80%以上,对标准强毒株和地方分离株均可产生有效免疫保护. |
| 关 键 词： | 传染性法氏囊病病毒 变异株 免疫原性 |
| 文章编号： | 1005-4545(2007)02-0164-04 |
| 修稿时间： | 2006年4月19日 |
Immunogenicity of epidemic strains of infectious bursal disease virus |
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| MA Zeng-jun,RUI Ping,LI Pei-guo,LIU Hua-ge,CUI Xue-wen,ZHANG Zhi-quan,DONG Shu-zhen.Immunogenicity of epidemic strains of infectious bursal disease virus[J].Chinese Journal of Veterinary Science,2007,27(2):164-167. | |
| Authors: | MA Zeng-jun RUI Ping LI Pei-guo LIU Hua-ge CUI Xue-wen ZHANG Zhi-quan DONG Shu-zhen |
| Abstract: | Ten strains of IBDV were Isolated from the different sick chicken farm in Hebei province,and identified by agar diffusion test.The immune protect test about the ten IBDV epidemic strains and E-JD2 immunogen against standard virulent virus IBDV-BC6/85,and attenuated vaccine strain D_78 against IBDV segregation strains,and the mutual immune test between IBDV segregation strains were performed.The result showed that the protect rate of D_78 to JD2,JD5 and JD10 IBDV strains decreased by 40%,50%,60% respectively.Immune protect rate reached 100% on JD2,E-JD2,JD5 against virulent virus.Mutual immune protect test showed that the protect rate of JD2 against the other strains was 80%.Indicating the JD2 strain could produce the valid immune protect against the standard virulent virus and epidemic strains. |
| Keywords: | infectious bursal disease virus variant immunogenicity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |