Comparison of amino acid profiles between rats subjected to forced running
and voluntary running exercises |
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Authors: | Rieko OKAME Keiko NAKAHARA Yumiko KATO Makoto BANNAI Noboru MURAKAMI |
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Institution: | 1)Department of Veterinary Physiology, Faculty of Agriculture, University of Miyazaki, Miyazaki 889–2192, Japan;2)Frontier Research Labs, Institute for Innovation, Ajinomoto Co., Inc., Kawasaki, Japan;3)Fundamental Technology Labs, Institute for Innovation, Ajinomoto Co., Inc., Kawasaki, Japan |
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Abstract: | It has been suspected that in comparison with glucose or fatty acids, the levels of amino
acids may readily change with different forms of exercise. In the present study, we
measured the concentrations of amino acids, glucose, triglycerides, total protein and
total cholesterol in the blood and/or cerebrospinal fluid (CSF) of rats subjected to
forced running exercise on a treadmill, and voluntary running exercise using a wheel, with
a constant running distance of 440 m. Rats that performed no running and rats subjected to
immobilization stress were used as controls. We observed a few significant changes in the
levels of plasma glucose, triglycerides, total protein and total cholesterol in all
groups. Whereas, plasma amino acid levels were significantly changed by exercise and
stress, especially during the light period. The plasma levels of many amino acids were
specifically increased by forced running; some were decreased by immobilization stress.
Few amino acids showed similar changes in their levels as a result of voluntary running.
In addition, there was a significant difference in the degree of amino acid imbalance
between blood and CSF. These results provide the first information on changes in levels of
amino acids in plasma and CSF resulting from forced and voluntary exercises. |
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Keywords: | behavior exercise physiology rat |
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