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Meet the corneal myofibroblast: the role of myofibroblast transformation in corneal wound healing and pathology |
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| Authors: | Kathern E Myrna Simon A Pot Christopher J Murphy† |
| Institution: | Department of Surgical Sciences, University of Wisconsin, School of Veterinary Medicine, Madison, WI, USA;, Schools of Medicine and Veterinary Medicine, University of California, Davis, CA, USA |
| Abstract: | In recent years the role of the myofibroblast in corneal wound healing has been extensively studied. The transformation of the corneal keratocyte to the fibroblast and myofibroblast phenotypes is a critical process in normal and pathologic corneal wound healing. This review will introduce this important transformation and its role in corneal wound healing and pathology. |
| Keywords: | cornea corneal wound healing myofibroblast stroma |