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南江黄羊GHR基因5′-调控区多态与体重性状相关性研究
引用本文:张春香,罗海玲,陈喻,张国俊,贾志海. 南江黄羊GHR基因5′-调控区多态与体重性状相关性研究[J]. 中国畜牧杂志, 2007, 0(15)
作者姓名:张春香  罗海玲  陈喻  张国俊  贾志海
作者单位:中国农业大学动物科技学院,山西农业大学 山西太谷030801,中国农业大学动物科技学院,四川南江黄羊育种科学研究所,四川南江黄羊育种科学研究所,中国农业大学动物科技学院,北京100094,北京100094,四川南江636600,四川南江636600,北京100094
基金项目:国家高技术研究发展计划资助(2002AA242051)
摘    要:试验采用PCR-SSCP方法检测392只南江黄羊和49只波尔山羊GHR基因5′-调控区多态性,并与体重性状进行关联分析。结果表明:GHR基因5′-调控区存在(G)10、(G)11与(G)14多态和(TG)13、(TG)14与(TG)17多态。经最小二乘分析,在2个山羊群体中基因型效应对初生重的影响不显著(P>0.05),对周岁体重影响显著,基因型BB所对应周岁体重的最小二乘均值显著高于基因型DD所对应的最小二乘均值(P<0.05)。

关 键 词:生长激素受体基因  体重性状  南江黄羊

Correlation between Polymorphisms of 5'-Flanking Region of GHR Gene and Body Weight of Nanjiang Huang Goats
ZHANG Chun-xiang,,LUO Hai-ling,CHEN Yu,ZHANG Guo-jun,JIA Zhi-hai. Correlation between Polymorphisms of 5'-Flanking Region of GHR Gene and Body Weight of Nanjiang Huang Goats[J]. Chinese Journal of Animal Science, 2007, 0(15)
Authors:ZHANG Chun-xiang    LUO Hai-ling  CHEN Yu  ZHANG Guo-jun  JIA Zhi-hai
Affiliation:ZHANG Chun-xiang1,2,LUO Hai-ling1,CHEN Yu3,ZHANG Guo-jun3,JIA Zhi-hai1
Abstract:The genotypes of 392 Nanjiang Huang goats and 49 Boer goats at 5' flanking region of GHR gene were detected by PCR-SSCP.The correlation between of the polymorphisms and body weight were analyzed.G repeat and GT repeat polymorphisms were identified at 5'flanking region of the GHR gene.The correlation analysis revealed that polymorphisms had a significant effect on body weight of 12 month.The BB genotype had higher body weight at 12 month than the DD genotype(P < 0.05) in Nanjiang Huang goats and Boer goats.There were no significant differences between different genotypes and birth weight in Nanjiang Huang goats and Boer goats.
Keywords:growth hormone receptor gene  body weight trait  Nanjiang Huang goats
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