| Genome-wide identification of functional enhancers and their potential roles in pig breedingOA |
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| 作者姓名： | Yinqiao Wu Yuedong Zhang Hang Liu Yun Gao Yuyan Liu Ling Chen Lu Liu David M.Irwin Chunhui Hou Zhongyin Zhou Yaping Zhang |
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| 作者单位： | 1. State Key Laboratory of Genetic Resources and Evolution, and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences;2. Kunming College of Life Science, University of Chinese Academy of Sciences;3. State Key Laboratory for Conservation and Utilization of Bio-resource in Yunnan, Yunnan University;4. School of Life Science, Yunnan University;5. Institute of Physical Science and Information Technology, Anhui University;6. Department of Laboratory Medicine and Pathobiology, University of Toronto;7. Department of Biology, School of Life Sciences,Southern University of Science and Technology;8. Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences |
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| 基金项目： | supported by the National Natural Science Foundation of China (32100502)； |
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| 摘 要： | Background: The pig is an economically important livestock species and is a widely applied large animal model in medical research. Enhancers are critical regulatory elements that have fundamental functions in evolution,development and disease. Genome-wide quantification of functional enhancers in the pig is needed.Results: We performed self-transcribing active regulatory region sequencing(STARR-seq) in the porcine kidney epithelial PK15 and testicular ST cell lines, and reliably identified 2576 ...
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