| Mapping short tandem repeats for liver gene expression traits helps prioritize potential causal variants for complex traits in pigsOA |
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| 作者姓名： | Zhongzi Wu Huanfa Gong Zhimin Zhou Tao Jiang Ziqi Lin Jing Li Shijun Xiao Bin Yang Lusheng Huang |
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| 基金项目： | supported by National Natural Science Foundation of China(31790413)；;supported by National Natural Science Foundation of China (31760657)； |
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| 摘 要： | Background: Short tandem repeats(STRs) were recently found to have significant impacts on gene expression and diseases in humans, but their roles on gene expression and complex traits in pigs remain unexplored. This study investigates the effects of STRs on gene expression in liver tissues based on the whole-genome sequences and RNA-Seq data of a discovery cohort of 260 F6 individuals and a validation population of 296 F7 individuals from a heterogeneous population generated from crosses among e...
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