| Estimates of genomic inbreeding and identification of candidate regions that differ between Chinese indigenous sheep breedsOA |
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| 作者姓名： | Jiaxin Liu Liangyu Shi Yang Li Liang Chen Dorian Garrick Lixian Wang Fuping Zhao |
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| 作者单位： | 1. Key Laboratory of Animal Genetics, Breeding and Reproduction (Poultry) of Ministry of Agriculture, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences;2. The Affiliated High School of Peking University;3. A.L.Rae Centre of Genetics and Breeding, Massey University |
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| 基金项目： | funded by the Natural Science Foundations of China (No.31572357) to FPZ； |
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| 摘 要： | Background: A run of homozygosity(ROH) is a consecutive tract of homozygous genotypes in an individual that indicates it has inherited the same ancestral haplotype from both parents. Genomic inbreeding can be quantified based on ROH. Genomic regions enriched with ROH may be indicative of selection sweeps and are known as ROH islands. We carried out ROH analyses in five Chinese indigenous sheep breeds; Altay sheep(n = 50 individuals),Large-tailed Han sheep(n = 50), Hulun Buir sheep(n = 150), Shor...
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