Serologic evidence of coronavirus infection in New York and New England dairy cattle with winter dysentery. |
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Authors: | H J Van Kruiningen V P Castellano A Torres R L Sharpee |
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Affiliation: | Department of Pathobiology, University of Connecticut, Storrs 06269. |
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Abstract: | Acute and convalescent sera were collected from 8 dairy herds with classic clinical features of winter dysentery. An enzyme-linked immunosorbent assay was used to measure coronavirus antibody titers, employing calf diarrhea coronavirus as antigen. Twenty-two of the 35 animals tested (63%) showed a greater than or equal to 4-fold seroconversion. Adult cattle in all 8 herds seroconverted. These findings complement previously reported immunoperoxidase and electron microscopic evidence, suggesting an etiologic role for an enteric coronavirus in this disease. |
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