| 穿琥宁注射液的急性毒性试验 |
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| 引用本文： | 曾艳,贺月林,陈薇,缪东. 穿琥宁注射液的急性毒性试验[J]. 动物医学进展, 2009, 30(1) |
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| 作者姓名： | 曾艳 贺月林 陈薇 缪东 |
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| 作者单位： | 湖南省微生物研究所,湖南,长沙,410009;湖南省微生物研究所,湖南,长沙,410009;湖南省微生物研究所,湖南,长沙,410009;湖南省微生物研究所,湖南,长沙,410009 |
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| 摘 要： | 通过腹腔注射法对小鼠给药,连续观察7 d,结果表明,穿琥宁注射液对小鼠的半数致死量(LD50)为757 mg/kg,LD50的95%可信限为861.8 mg/kg～701.7 mg/kg,说明穿琥宁注射液毒性小,应用安全.
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| 关 键 词： | 穿琥宁注射液 小鼠 LD50 |
Study on Acute Toxicity of Potassium Dehydroandrograpolide Succinate Injection in Mice |
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| ZENG Yan,HE Yue-lin,CHEN Wei,MIU Dong. Study on Acute Toxicity of Potassium Dehydroandrograpolide Succinate Injection in Mice[J]. Progress In Veterinary Medicine, 2009, 30(1) |
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| Authors: | ZENG Yan HE Yue-lin CHEN Wei MIU Dong |
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| Affiliation: | Microbiology Research Institute of Hunan;Changsha;Hunan;410009;China |
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| Abstract: | The mice were given potassium dehydroandrograpolide succinate injection by intraperitoneal injection,and observed for 7 days continuously.Results indicated that the LD50 of potassium dehydroandrograpolide succinate injection in mice was 757 mg/kg,95%confidence limits was 861.8 mg/kg-701.7 mg/kg.All these results confirmed that no acute toxcity was found in potassium dehydroandrograpolide succinate injection. |
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| Keywords: | LD50 |
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