饲用碘酸钙/海藻酸钠微球的制备

为提高碘酸钙在饲料中的稳定性，以碘酸钙为芯材，海藻酸钠（Ｓｏｄｉｕｍａｌｇｉｎａｔｅ，ＳＡ）为壁材，纳米碳酸钙为交联剂，将碘酸钙分散于液体石蜡中，采用内源乳化法制备了碘酸钙／海藻酸钠凝胶微球．采用傅里叶红外光谱和扫描电子显微镜对碘酸钙／海藻酸钠凝胶微球进行了表征，并通过单因素法系统考察了碘酸钙／海藻酸钠凝胶微球制备工艺对其载药率和包封率的影响．结果表明，碘酸钙以晶体形式负载于碘酸钙／海藻酸钠凝胶微球上；在海藻酸钠质量浓度为１２ｇ•Ｌ－１，纳米碳酸钙质量分数为ＳＡ的１／２，Ｓｐａｎ８０质量分数为２％，酸钙物质的量比为６.９∶１，碘酸钙质量为１.２ｇ，油相搅拌速度５００ｒ?ｍｉｎ－１，油水体积比为３∶１，乳化３０ｍｉｎ，富集９０ｍｉｎ和交联２５ｍｉｎ条件下工艺最优，其制备的碘酸钙／海藻酸钠凝胶微球载药率和包封率分别为４１.０％和７１.８％．

Preparation of sodium alginate microspheressupported calcium iodate for feeds

In order to improve the stability of calcium iodate in feeds，Calcium iodate have been distribu-ted into liquid paraffin at first，then the microsphere of calcium iodate( Ca( IO 3 )2 /SA microsphere) wereprepared by emulsification/internal gelation with sodium alginate as wall material and Nano-calcium car-bonate as cross linker． The Ca( IO 3 )2 /SA microspheres were characterized by FT-IR and SEM，and theinfluence of preparation conditions of Ca( IO 3 )2 /SA microsphere on the loading content of calcium iodate( LC) and encapsulation efficiency ( EE) was studied systematically by the single-factor method． The re-sults showed that the loaded calcium iodate was loaded in crystalline form in microspheres． The optimizedcondition of preparation of Ca( IO 3 )2 /SA microsphere were as follows: sodium alginate concentration12 g·L－1 ，Nano-calcium 1/2，Span80 2%，acid-calcium substance ratio 6. 9∶ 1，calcium iodate mass1. 2 g，oil phase stirring speed 500 r·min－1 ，oil-water volume ratio 3∶ 1，emulsification time 30 min，enrichment time 90 min，crosslinking time 25 min． The loading content ( LC) and encapsulation efficiency( EE) of Ca( IO 3 )2 /SA microsphere in the optimized condition were 41. 0% and 71. 8%，respectively．