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Immunological treatment of cough occurring in dogs with dirofilariosis.
Authors:M Hayasaki  A Harayama  H Seki  K Konno  I Ohishi
Institution:Department of Internal Medicine and Parasitology, School of Veterinary Medicine, Tokyo University of Agriculture and Technology, Japan.
Abstract:A persistent, spasmic and productive cough known as filarial cough often occurs in dogs with dirofilariosis, and has been considered to be the consequence of an allergic response to Dirofilaria immitis. Twenty-one dogs with filarial cough were subcutaneously injected with worm antigen (200 micrograms of protein concentration) extracted from adult D. immitis once a day for 5 days. These injections were effective for 17 (81%) of the dogs, resulting in a complete cure for 7 dogs and marked improvement for 10 dogs.
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