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In vitro enhancement by CpG ODN of phagocytic activity of rainbow trout head kidney phagocytes against fish pathogen Vibrio ordalii, but not against polystyrene particles
Authors:Nakatani Masahiro  Iwasaki Tadashi  Watarai Shinobu  Kodama Hiroshi
Institution:Laboratory of Veterinary Immunology, Course of Veterinary Science, Graduate School of Life and Environmental Science, Osaka Prefecture University, Sakai, Osaka, Japan.
Abstract:Rainbow trout (Oncorhynchus mykiss) head kidney phagocytes precultured with a synthetic cytidine-phosphate-guanosine (CpG) oligodeoxynucleotide (ODN) displayed significantly higher phagocytic activity against Vibrio ordalii than phagocytes precultured with non-CpG ODN. However, head kidney phagocytes precultured with CpG ODN did not show enhanced phagocytic activity against polystyrene particles.
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