中雏鸡白痢病实验病理研究

鸡白痢沙门氏菌感染中雏鸡可造成少数鸡急性死亡,多数鸡生长缓慢。感染鸡接种菌的检出率:静脉注射组73.7%,口服组55%,并随血清特异性抗体的增高而下降。感染鸡的肝、脾病变突出,感染后第21天部分病例肝呈现淀粉样物沉积,证实了有关文献中沙门氏菌引起禽类淀粉样物沉积的推论,并阐明了中雏鸡白痢病后期死于腹水和肝破裂的机理。根据各种血清蛋白的消长、肝功指标变化;骨髓、腔上囊和脾脏等器官的病变,提示了感染鸡的肝脏和免疫器官的机能低下是中雏鸡白痢病易受逆境应激因素作用造成伴发感染和大量死亡的内在原因,从而为本病诊断和防制提供了重要依据。

STUDIES ON THE PATHOLOGY OF EXPERIMENTALLY PRODUCED PULLORUM DISEASE IN 3-6 WEEK OLD CHICKENS

Our experiments showed that pullorum disease could be produced by e- xperimental exposure of 3 week old chickens to Salmonella pullorum and that the disease resulted in an acute death in some and a growth stunt in a majority of chickens.The isolation rate of the pathogen was 73.7 percent and 55 percent in groups given intravenously and orally respectively and decreased in accordance with the increase of the serum antibody titre.The most severe lesions were seen in the liver and spleen of experimentally inf-...