Antioxidant,Antimicrobial and Genotoxicity Screening of Hydro-alcoholic Extracts of Five Serbian <Emphasis Type="Italic">Equisetum</Emphasis> Species |
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| Authors: | Vesna Milovanović Niko Radulović Zoran Todorović Miroslava Stanković Gordana Stojanović |
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| Institution: | (1) Technical High School, Kosančićeva 28, 37000 Kruševac, Serbia;(2) Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000 Niš, Serbia;(3) Faculty of Technology, University of Niš, Bulevar oslobođenja 124, 16000 Leskovac, Serbia;(4) Physical Chemistry Laboratory, Institute of Nuclear Science, Vinča, 11000 Belgrade, Serbia |
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| Abstract: | The hydro-alcoholic extracts of five Equisetum species, E. arvense L., E. sylvaticum L., E. fluviatile L., E. palustre L. and E. telmateia Ehrh., growing-wild in Serbia were evaluated for their genotoxicity, antimicrobial activity, antioxidant capacity and the results
related to the total phenol content and HPLC flavonoid profiles. The total phenol content was 92–349 μmol expressed as equivalents
of chlorogenic acid per g of dried plant material. Main identified compounds were kaempferol-, quercetin- glycosides and caffeic
acid derivatives. E. telmateia extract showed the greatest antioxidant capacity. Almost all tested microorganisms demonstrated some degree of sensitivity
to the examined extracts. All tested extracts at 62.5 μg/ml showed higher incidence of micronucleus formation than in the
control sample. The obtained data allowed mutual comparison of examined species and their assessment as possible sources of
antioxidants, antimicrobials and/or genotoxic substances. |
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| Keywords: | Antimicrobial activity Antioxidant capacity Equisetum sp Flavonoids Genotoxicity Hydro-alcoholic extracts |
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