| 骨基质明胶预防人工关节无菌性松动的实验研究 |
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| 引用本文： | 游洪波,陈安民,孙淑珍,林柏云.骨基质明胶预防人工关节无菌性松动的实验研究[J].湛江医学院学报,1999,17(2):105-107. |
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| 作者姓名： | 游洪波 陈安民 孙淑珍 林柏云 |
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| 作者单位： | [1]广东医学院附属医院骨科 [2]同济医科大学同济医院 |
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| 摘 要： | 目的：研究骨基质明胶（ＢＭＧ）防治人工关节无菌性松动的可行性。方法：制备兔ＢＭＣ及陶瓷人工股骨头。大白兔４０只，随机分成两组，行右人工股骨头置换，一组植入ＢＭＣ，另一组不植ＢＭＣ作为对照，并以不同时期作生物力学测定，组织学检查，立体显微摄影和电子探针检测，以了解人工关节周围的成骨情况。
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| 关 键 词： | 骨基质 明胶 人工关节 实验 |
| 修稿时间： | 1998-10-19 |
Prevention of aseptic loosening after artificial joint replacement by bone matrix gelatin |
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| YouHongbo,ChenAnmin,SunShuzhen,etal.Prevention of aseptic loosening after artificial joint replacement by bone matrix gelatin[J].Journal of Guangdong Medical College,1999,17(2):105-107. |
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| Authors: | YouHongbo ChenAnmin SunShuzhen etal |
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| Institution: | YouHongbo1,ChenAnmin2,SunShuzhen3,etal |
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| Abstract: | Objective: Topreventasepticlooseningafterartificialjointreplacementbybonematrixgelatin(BMG). Methods: BMGandrabbitprosthesisoffemoralheadweremade.Fortyrabbits,operatedonthemforrightartificialreplacement,weredividedrandomlyintotwogroups.BMGwasimplantedintorabbitprothesisinonegroup,andothergroupwasnotascontrolgroup.Thetissuesaroundprosthesiswereexaminedbybiologicdynamictest,histologicexamination,dimensionalmicroscopy,andelectricprobeXraymicroscopyanalysis. Results: ThepulloutstrengthofBMGgroupwashigherthanthatofthecontrolgroup.TheosteoinductivequantityandqualityofBMGgroupwereobviouslyhigherthanthoseinthecontrolgroup. Conclusion: BMGcouldaccelerateperiprosthesesosteoinductionandpreventasepticlooseningofcementlessprosthesis. |
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| Keywords: | bonematrix gelatin artificialjointreplacement experiment |
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