| 高通量筛选法对普洱茶降血糖血脂作用的研究 |
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| 引用本文： | 张冬英,刘仲华,施兆鹏,刘亚林,付冬和. 高通量筛选法对普洱茶降血糖血脂作用的研究[J]. 茶叶科学, 2006, 26(1): 49-53 |
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| 作者姓名： | 张冬英 刘仲华 施兆鹏 刘亚林 付冬和 |
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| 作者单位： | 湖南农业大学天然产物研究中心;湖南农业大学动物科技学院,湖南,长沙,410128 |
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| 摘 要： | 利用高通量筛选法寻找普洱茶降血糖血脂作用的活性成分的研究。实验以SMMC-7721细胞为模型,确定普洱茶各样品的合适筛选浓度为50μg/ml,并以此浓度对激活PPARα、PPARδ、PPARγ受体的活性进行筛选。结果发现,普洱茶醇提物对PPARδ受体有激活作用,有潜在的降血糖和降血脂作用的可能。
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| 关 键 词： | 高通量筛选 普洱茶 血糖 血脂 |
| 文章编号： | 1000-369X（2006）01-049-05 |
| 收稿时间： | 2005-09-13 |
| 修稿时间： | 2005-10-31 |
Study on Blood Glucose-Depressing and Blood Lipid-Depressing Function of Pu'er Tea by High Throughput Screening Method |
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| ZHANG Dong-ying,LIU Zhong-hua,SHI Zhao-peng,LIU Ya-lin,FU Dong-he. Study on Blood Glucose-Depressing and Blood Lipid-Depressing Function of Pu'er Tea by High Throughput Screening Method[J]. Journal of Tea Science, 2006, 26(1): 49-53 |
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| Authors: | ZHANG Dong-ying LIU Zhong-hua SHI Zhao-peng LIU Ya-lin FU Dong-he |
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| Affiliation: | 1. Natural Products Institute of Hunan Agricultural University; 2. College of Animal Science and Technology, Changsha 410128. China |
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| Abstract: | Discovering the active substances of Pu’er Tea on blood glucose depressing and blood lipid-depressing function was studied by high throughput screening method.In this experiment,SMMC-7721 cells were used as the model,the screening concentration of samples was established at to 50 μg/ml,and the activity of Pu’er Tea on activing PPARα、PPARδ、PPARγ was screening.The result showed that Pu’er Tea ethanol extract can active PPARδand may be have the function of lowering blood glucose and blood lipid depressing function. |
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| Keywords: | high throughput screening Pu’er tea blood glucose blood lip |
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